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Additionally, a large number of studies have investigated the effects of MC ligands on macronutrient intake and most studies [but not all ( Additionally, in studies investigating the sensitivity of the melanocortin system during diet-induced obesity conflicting data have been described, as obese animals show both decreased ( To distinguish between the effect of obesity and diet composition, we use a diet with separate food components, rather than pellet diets that differ in fat and sugar content
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